bioflow™ IO (Intra-Operative)
A multipurpose amniotic fluid therapy that has been processed for use in a variety of operative procedures. It has potential applications in foot and ankle surgery and other medical specialties and may be conveniently applied directly to the site of injury, inflammation and pain. There is no need to dilute or manipulate the liquid before application, thereby providing maximum strength delivery to the injured or inflamed area. Its potential clinical applications include:
- Augmentation of tendon, fasciae, ligament and capsular repair
- Chronic neuritis and pain
- Complement tissue repair
- Bioflow™ IO is available in four usefully calibrated sizes
Bioflow™ IO is designed for surgical use to supplement damaged or inadequate connective tissue. Amniotic fluid contains a broad spectrum of growth factors and cytokines (fig. 1) that are known to play important roles in wound healing, cell proliferation and migration, and tissue protection and repair4. These molecules work to aid in the body’s own rejuvenation and healing processes.
|FLOWIO0200||X Large, 2.00ml|
Amniotic fluid is rich in the components that are believed to contribute to a wound healing response, characterized by minimal inflammatory activity and regenerative rather than scar-mediated healing. These components work to kick-start the body’s own rejuvenation and healing processes.
Easy To Apply
Bioflow™ IO is provided in an easy to apply, flowable form, for precise delivery throughout the intended surgical site. Bioflow™ is all-natural and does not contain storage additives that require dilution prior to use. However, it may be mixed with several solutions to extend the volume being applied.
Amniotic fluids are considered immune privileged, meaning they induce little or no immune response in the patient. Adverse immune responses may lead to complications. No blood typing or donor matching are required.
Bioflow™ is received in a validated shipping container on dry ice. It may be kept in the shipping container for up to 72, 96 or 118 hours (as indicated on the box), or moved to a freezer for storage at -80°C ± 15°C with a 2 year shelf life.
All Natural Protection
Safe and 100% natural, Bioflow™ IO contains no harmful additives. As a result, there is no need to dilute or manipulate the liquid before application, providing maximum strength delivery to the injured or inflamed area.
The donor tissue is recovered and processed aseptically, in full accordance with all FDA and AATB guidelines and quality assurance standards in a controlled environment. All Novastep allograft tissue products have been subjected to microbiological studies at recovery and final packaging.
fig. 1 Growth Factors and Cytokines Present in Allograft
4. Bazrafshan A, et al. Activation of mitosis and angiogenesis in diabetes-impaired wound healing by processed human amniotic fluid. Journal of Surgical Research 188 (2014) 545-5521.